Letter regarding “Sugammadex vs neostigmine in post-anesthesia recovery: A systematic review and meta-analysis”
Tuhin Mistry, Abhijit Sukumaran Nair · 2025
Read Letter regarding “Sugammadex vs neostigmine in post-anesthesia recovery: A systematic review and meta-analysis” by Tuhin Mistry, Abhijit Sukumaran Nair (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12974217.txt.
Description
Tuhin Mistry and Abhijit Sukumaran Nair offer a 2025 letter on a review that compared two drugs for reversing muscle blockade after anesthesia. The review found sugammadex gave faster recovery and less leftover blockade than neostigmine. The letter writers praise the synthesis but warn that pooled results may mislead.
Many outcomes varied hugely across studies, with a shared variance measure often over 90 percent. That spread may hide real gaps in anesthesia technique, blockade depth, and recovery care. They note that airway safety also turns on how deep the sedation is at reversal, not only on nerve measures. Mixed reporting of time effects needs cleaning up too. They ask for cautious readings and sharper subgroup work.
Catalog record
| CREATOR | Tuhin Mistry, Abhijit Sukumaran Nair |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 5 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |