Effect of pretransplant spleen volume on the prognosis of acute myeloid leukemia treated with allogeneic hematopoietic stem cell transplantation

Weiwei Liu, Bingjie Liu, Lihou Pang, Lixia Zhou, Fuxu Wang, Xuejun Zhang, Ying Wang · 2026

Read Effect of pretransplant spleen volume on the prognosis of acute myeloid leukemia treated with allogeneic hematopoietic stem cell transplantation by Weiwei Liu, Bingjie Liu, Lihou Pang, Lixia Zhou, Fuxu Wang, Xuejun Zhang, Ying Wang (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12953115.txt.

Description

Weiwei Liu and six co-authors looked back in 2025 at whether spleen size before a stem cell transplant predicts survival in acute myeloid leukemia. The hosted text dates the work to 2025, though the catalog lists 2026. The team reviewed fifty-eight patients who received donor transplants at a Hebei hospital from 2017 to 2022. Spleen size was judged against the range in 120 healthy people.

Patients with enlarged spleens lived shorter lives and had higher death rates without relapse. Relapse itself, graft take, and graft-versus-host disease did not differ by spleen size. Adjusted models kept spleen size as an independent risk factor, with a viral infection also mattering. The authors say a large spleen before transplant should warn care teams of a harder course.

Catalog record

CREATORWeiwei Liu, Bingjie Liu, Lihou Pang, Lixia Zhou, Fuxu Wang, Xuejun Zhang, Ying Wang
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE30 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12953115

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