Genomic epidemiology of Helicobacter pylori in regions with high and low risk of gastric cancer, Colombia

Kevin Guzman, Danilo Igua, Harold Mauricio Casas Cruz, Alvaro Pazos, Arsenio Hidalgo · 2026

Read Genomic epidemiology of Helicobacter pylori in regions with high and low risk of gastric cancer, Colombia by Kevin Guzman, Danilo Igua, Harold Mauricio Casas Cruz, Alvaro Pazos, Arsenio Hidalgo (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12932587.txt.

Description

Kevin Guzman and co-authors read the genomes of Helicobacter pylori across Colombian ground where stomach cancer rates split sharply. The bacterium infects most of the world and drives stomach cancer, yet few carriers fall ill. In Nariño, infection is near universal on both the Andean heights and the Pacific coast, while cancer rates part by a wide gulf.

Their study joins death records from dozens of towns with genome reads of the bacterium's virulence genes. Higher ground tracks higher cancer deaths. Two local bacterial lineages stand out, one Andean and one coastal, with gene flow between them. The split helps crack the long-named Colombian enigma of risk.

Catalog record

CREATORKevin Guzman, Danilo Igua, Harold Mauricio Casas Cruz, Alvaro Pazos, Arsenio Hidalgo
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE33 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12932587

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