A defined bacterial consortium and spatial transcriptomics highlight the complex interaction between Campylobacter jejuni and the murine intestine

Siddhi Chitre, Raad Z Gharaibeh, Christian Jobin · 2025

Read A defined bacterial consortium and spatial transcriptomics highlight the complex interaction between Campylobacter jejuni and the murine intestine by Siddhi Chitre, Raad Z Gharaibeh, Christian Jobin (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12931722.txt.

Description

Siddhi Chitre, Raad Gharaibeh, and Christian Jobin study, in 2025 mouse work, how a set gut crew shapes the reply to a food-poison germ. Germ-free mice prone to gut flare were seeded with a fixed crew of thirteen gut kinds, with or without the target germ. Place-mapped gene reads then charted the fight in the colon's zones.

With the germ aboard, guts flared hard and flare genes rose, while two crew kinds swelled. Maps showed immune replies and lining rework pinned to set zones. Germ kinds that sat on tissue swayed host genes in unlike ways, germ by germ. The team backs fixed crews plus place maps to unpick such three-way play.

Catalog record

CREATORSiddhi Chitre, Raad Z Gharaibeh, Christian Jobin
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE61 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12931722

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