Dormant yet dangerous: the role of cell rest in perseverance
Anamélia Lorenzetti Bocca, Gabriélly Bindo Trindade, Rafaela L.L. Souza, Larissa Fernandes · 2025
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Description
Anamélia Lorenzetti Bocca and three co-authors reviewed in two thousand twenty-five how dormant cells help infections and tumours persist. Dormancy is a survival trick: cells cut activity and growth to ride out stress such as dryness, low oxygen, scarce food, or immune attack. It is reversible, so hidden cells can wake later.
Tumour cells use it to linger in tissue, and fungi use it to spread. The review centres on the tuberculosis bacterium and a yeast, Cryptococcus, which can sleep inside a host for years. Fat burning and its genes help them endure. Care must hit both active and dormant cells, the authors argue, for lasting cure.
Catalog record
| CREATOR | Anamélia Lorenzetti Bocca, Gabriélly Bindo Trindade, Rafaela L.L. Souza, Larissa Fernandes |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 34 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |