Glycyrrhiza polysaccharide attenuates Neospora caninum-induced intestinal epithelial cell damage by the C/EBPβ/IL-17/TNF signaling pathway
Shuai Wang, Sudan Meng, Yongsheng An, Weifeng Qian, Yanbo Ma, Shuai Guo, Cai Zhang · 2026
Read Glycyrrhiza polysaccharide attenuates Neospora caninum-induced intestinal epithelial cell damage by the C/EBPβ/IL-17/TNF signaling pathway by Shuai Wang, Sudan Meng, Yongsheng An, Weifeng Qian, Yanbo Ma, Shuai Guo, Cai Zhang (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12884399.txt.
Description
Shuai Wang and co-authors tested a licorice-root sugar compound as a shield for gut cells against a parasite, in a paper the text dates to 2025. The catalog lists 2026, but the head gives 2025. The parasite damages the gut lining of farm animals and stirs deep inflammation. The team worked with cow gut cells in dishes and with infected mice. Gene reads showed which pathways the parasite switches on.
In dishes, pre-treating cells with the compound kept more cells alive and cut signs of membrane damage. The parasite had lit up two swelling pathways and a set of signal genes. The compound dimmed a key switch factor and several swelling genes in reply. In mice, a low dose cut gut bleeding and swelling, and lowered parasite counts in gut and brain. The authors name the pathway chain they traced as the basis for further work.
Catalog record
| CREATOR | Shuai Wang, Sudan Meng, Yongsheng An, Weifeng Qian, Yanbo Ma, Shuai Guo, Cai Zhang |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 19 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |