Phase-targeted erythropoietin derivatives for traumatic brain injury: bridging mechanisms to precision therapy
Yujin Sun, Bo Song, Yonglei Zhang, Yan Zhang, Lu Zhou · 2026
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Description
Yujin Sun and co-authors wrote a review, published in 2025, on timed drug forms for brain injury from a blow or crash. Harm after such injury comes in waves, from fast cell stress to later vessel repair. A hormone that guards cells in animal tests also drives red cell growth, which has blocked its use in patients.
The review covers four reworked forms of the hormone that keep the guard effect but drop the red cell drive. Each form is matched to the injury phase it suits best. Trials so far hint at lower short term death rates with no clear gain in function. The authors lay out test plans for phase matched care built on these forms.
Catalog record
| CREATOR | Yujin Sun, Bo Song, Yonglei Zhang, Yan Zhang, Lu Zhou |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 38 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |