Efficacy and safety of fractional CO2 laser therapy combined with triamcinolone acetonide injection for hypertrophic scar: a preliminary systematic review and meta-analysis
Jianfeng Zhang, Mengke Wu, Cong Liu, Xiaochen Zhu, Qin Guo, Cheng Tan · 2026
Read Efficacy and safety of fractional CO2 laser therapy combined with triamcinolone acetonide injection for hypertrophic scar: a preliminary systematic review and meta-analysis by Jianfeng Zhang, Mengke Wu, Cong Liu, Xiaochen Zhu, Qin Guo, Cheng Tan (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12872559.txt.
Description
Jianfeng Zhang and co-authors review combined scar treatment in a paper whose text is dated 2025. Hypertrophic scars are thick, raised scars that can itch and hurt. One common treatment injects a steroid drug into the scar, and fractional carbon dioxide laser therapy is another. The team asked whether using both together beats the injection alone.
They searched eight databases for randomized trials and pooled nineteen studies with 1,775 patients. The combined treatment cut scar scale scores, itch, pain, and scar thickness by clear margins over injection alone, and it lowered a growth signal in the blood. Safety outcomes were also reviewed, and evidence quality was graded. The authors call the review preliminary, but the pooled edge for combined care is consistent.
Catalog record
| CREATOR | Jianfeng Zhang, Mengke Wu, Cong Liu, Xiaochen Zhu, Qin Guo, Cheng Tan |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 39 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |