Mangiferin: a novel hepatoprotective for liver cirrhosis via modulation of histological, cellular, biochemical, inflammatory markers and oxidative stress
Khaled Abdul-Aziz Ahmed, Suhayla Hamad Shareef, Haween Toufiq Nanakaly, Mohammed A. Ali, Derin Nabaz Fisal, Peshawa Yunis Aziz, Nabaz Fisal Shakir Agha, Mahmood Ameen Abdulla, Ahmed A. Salman · 2025
Read Mangiferin: a novel hepatoprotective for liver cirrhosis via modulation of histological, cellular, biochemical, inflammatory markers and oxidative stress by Khaled Abdul-Aziz Ahmed, Suhayla Hamad Shareef, Haween Toufiq Nanakaly, Mohammed A. Ali, Derin Nabaz Fisal, Peshawa Yunis Aziz, Nabaz Fisal Shakir Agha, Mahmood Ameen Abdulla, Ahmed A. Salman (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12866065.txt.
Description
Khaled Ahmed and co-authors test whether mangiferin, a mango compound, can shield rat livers from chemical scarring, in a 2025 study. Cirrhosis grows when star-shaped liver cells wake and lay down scar. Thirty rats split into five groups: healthy, poisoned with thioacetamide, poisoned plus a known liver drug, and poisoned plus mangiferin at two doses, all for two months. A safety arm first showed high doses brought no toxic signs.
The poisoned livers came out rough and knotted, with dead patches, scar bands, and swollen stress signals. Their blood marks of liver work sank, and their guard enzymes fell while flame signals rose. Mangiferin-fed rats kept a far tidier liver: smoother surface, milder cell harm, and stress and flame marks pulled back toward calm. The authors name the compound a candidate liver guard, with dose work and human proof still ahead.
Catalog record
| CREATOR | Khaled Abdul-Aziz Ahmed, Suhayla Hamad Shareef, Haween Toufiq Nanakaly, Mohammed A. Ali, Derin Nabaz Fisal, Peshawa Yunis Aziz, Nabaz Fisal Shakir Agha, Mahmood Ameen Abdulla, Ahmed A. Salman |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 47 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |