Double metastatic cancer with lung and urothelial carcinoma responding to enfortumab vedotin: a case report and review of the literature

Magali Ravoire, Léa Vazquez · 2025

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Description

Magali Ravoire and Léa Vazquez report a rare double cancer case in a 2025 paper. A man aged seventy-four had lung cancer spread to distant sites. During first-line care for the lung cancer, a second cancer arose in his urinary tract lining.

When the second cancer came back after standard drugs, doctors started a targeted drug pair built to home on nectin-4. The urinary tumors cleared fully, and the lung tumors shrank in part. Care stopped after sixteen months due to mild nerve harm, while the full response held. The team note this dual response had not been reported before. It hints the drug target may matter beyond its usual cancer.

Catalog record

CREATORMagali Ravoire, Léa Vazquez
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE15 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12865975

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