Exosomes from LPS-pretreated BMSCs treated periodontitis via improving oxidative stress
Chenyu Xu, Hanping Wang, Wenqi Dong, Wen Cheng, Yuran Su, Qiang Yang, Yue Wang, Yanhong Zhao · 2025
Read Exosomes from LPS-pretreated BMSCs treated periodontitis via improving oxidative stress by Chenyu Xu, Hanping Wang, Wenqi Dong, Wen Cheng, Yuran Su, Qiang Yang, Yue Wang, Yanhong Zhao (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12865969.txt.
Description
Chenyu Xu and co-authors test whether tiny packets from pretreated stem cells can heal gum disease, in a 2025 study. The disease is tied to oxidative stress and failing cell power plants. Stem cells from bone marrow release packets called exosomes. Priming the cells with a bacterial toxin changed those packets.
The team extracted the packets and checked their size and markers. Safety tests covered cell growth, movement, and uptake. Stressed cells and animals with gum disease were treated with primed and unprimed packets. The primed packets eased oxidative stress and power plant trouble more strongly. A cell-free therapy of this kind could calm gum disease without transplanting live cells.
Catalog record
| CREATOR | Chenyu Xu, Hanping Wang, Wenqi Dong, Wen Cheng, Yuran Su, Qiang Yang, Yue Wang, Yanhong Zhao |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 55 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |