Proliferation-cycle gene signatures predict immune landscape and prognosis in lung adenocarcinoma

Chenjing Lin, Man Zhang, Pan Sun, Yulin He, Yi Tian, Wenwen Li, Shengyan Pu, Jizhuang Luo, Kai Wang · 2025

Read Proliferation-cycle gene signatures predict immune landscape and prognosis in lung adenocarcinoma by Chenjing Lin, Man Zhang, Pan Sun, Yulin He, Yi Tian, Wenwen Li, Shengyan Pu, Jizhuang Luo, Kai Wang (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12864599.txt.

Description

Chenjing Lin and co-authors hunt gene signs in lung adenocarcinoma in 2025. This lung cancer still carries a poor outlook despite better tests and drugs. Genes that drive cell growth and division also shape the immune scene around tumors. The team mined a large cancer genome atlas for growth cycle genes tied to risk.

They found a small set of risk genes, most switched up and one switched down. The set was checked in a national genome center data set as well. The signs track the immune landscape of the tumor and how patients fare. They may also hint at who will respond to immune based therapy.

Catalog record

CREATORChenjing Lin, Man Zhang, Pan Sun, Yulin He, Yi Tian, Wenwen Li, Shengyan Pu, Jizhuang Luo, Kai Wang
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE43 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12864599

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