The Effectiveness of Topical Keratolytics (Alpha Hydroxy Acids/Beta Hydroxy Acids/Urea) in Treating Keratosis Pilaris: A Review of the Literature

Eleftheria Dampa · 2025

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Description

Eleftheria Dampa reviews the proof for creams that loosen rough skin in keratosis pilaris, a common and harmless condition of bumpy hair follicles. Her 2025 review covers three groups of skin creams: alpha hydroxy acids, beta hydroxy acids, and urea. The bumps most often appear on the upper arms, thighs, and buttocks, and they trouble many people for how they look and feel.

All three cream types showed potential benefit, and they remain sensible first choices for easing symptoms. Yet the proof base is thin. Trials were small, measured results in unlike ways, rarely hid who got which cream, and seldom followed patients for long. Little is known about keeping gains over time, or about which cream suits red versus rough forms. Dampa calls for stronger trials before firm guidance can be given.

Catalog record

CREATOREleftheria Dampa
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE30 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12860576

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