Cadherin 1 germline mutation co-occurs with medullary thyroid cancer and choroid plexus papilloma: A case report and review of literature
Vijay Nitturi, Sricharan Gopakumar, Hsiang-Chih Lu, Akash J. Patel · 2025
Read Cadherin 1 germline mutation co-occurs with medullary thyroid cancer and choroid plexus papilloma: A case report and review of literature by Vijay Nitturi, Sricharan Gopakumar, Hsiang-Chih Lu, Akash J. Patel (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12860305.txt.
Description
Vijay Nitturi and co-authors report a young woman whose two rare tumors share an inherited gene fault, in work from 2025. She had thyroid medullary cancer, then a benign growth in a brain fluid space. The pairing had rarely been described together before.
Scans found a lobed mass in the fourth ventricle after she reported on-and-off headaches. Surgery removed the growth, and tissue tests named it a choroid plexus papilloma. Tumor gene tests found no unique changes, but inherited testing found a fault in a tumor guard gene called CDH1. The authors review past cases and argue the gene may predispose to both tumors.
Catalog record
| CREATOR | Vijay Nitturi, Sricharan Gopakumar, Hsiang-Chih Lu, Akash J. Patel |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 9 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |