Quercetin/curcumin suppresses pancreatic tumor growth and enhances chemosensitivity in a Capan-1 xenograft model
Gökhan Varlı, Fatma Azize Budak Yıldıran, Özgür Albuz, Necdet Sağlam, Mustafa Türk · 2025
Read Quercetin/curcumin suppresses pancreatic tumor growth and enhances chemosensitivity in a Capan-1 xenograft model by Gökhan Varlı, Fatma Azize Budak Yıldıran, Özgür Albuz, Necdet Sağlam, Mustafa Türk (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12860013.txt.
Description
Gökhan Varlı and four co-authors test two plant compounds against pancreatic cancer grown in mice, in this 2025 study. The cancer is among the deadliest, resisting standard drugs, while quercetin and curcumin are known for gentle, cancer fighting properties. Thirty-four mice carrying human tumor grafts were split into six groups for a month of treatment.
The compound pair, given by mouth or injection, held tumor growth about forty percent below untreated controls, matching the standard drug cisplatin alone. Pairing the compounds with cisplatin did better still, and dead tissue inside tumors grew. A group dosed before tumors were planted tested prevention. The authors read the results as evidence that the plant pair can support chemotherapy against a stubborn cancer, pending human trials.
Catalog record
| CREATOR | Gökhan Varlı, Fatma Azize Budak Yıldıran, Özgür Albuz, Necdet Sağlam, Mustafa Türk |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 63 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |