MRI-based evaluation for predicting pathological response and monitoring reactive angioma evolution in triple-negative breast cancer undergoing neoadjuvant chemoimmunotherapy
Luyi Lin, Jinlong Zheng, Fan Yang, Ke Zuo, Jiayin Zhou, Guanhua Su, Xiaowen Ma, Chao You, Yajia Gu · 2025
Read MRI-based evaluation for predicting pathological response and monitoring reactive angioma evolution in triple-negative breast cancer undergoing neoadjuvant chemoimmunotherapy by Luyi Lin, Jinlong Zheng, Fan Yang, Ke Zuo, Jiayin Zhou, Guanhua Su, Xiaowen Ma, Chao You, Yajia Gu (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12859831.txt.
Description
Luyi Lin and co-authors study in 2025 whether MRI scans can predict response to combined chemotherapy and immune therapy in triple negative breast cancer. This aggressive cancer type gains from treatment given before surgery, yet scan based prediction of full response is little explored. The team also tracks a side effect in which new blood vessel growths appear during care.
Their data pool several trials run at one center over recent years, covering dozens of patients. Scan features from standard reporting terms and from measured water movement across the whole tumor were joined with tissue results. Layered statistical models searched for traits that independently foresee a complete response, and a combined model was built from the strongest ones. Vessel changes over the course of therapy were followed with standard tests for paired data.
Catalog record
| CREATOR | Luyi Lin, Jinlong Zheng, Fan Yang, Ke Zuo, Jiayin Zhou, Guanhua Su, Xiaowen Ma, Chao You, Yajia Gu |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 38 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |