Enhanced sucrose production by controlling carbon flux through CfrA expression in Synechocystis sp. PCC 6803
María Teresa Domínguez-Lobo, Pablo Ortega-Martínez, Francisco J. Florencio, M. Isabel Muro-Pastor · 2025
Read Enhanced sucrose production by controlling carbon flux through CfrA expression in Synechocystis sp. PCC 6803 by María Teresa Domínguez-Lobo, Pablo Ortega-Martínez, Francisco J. Florencio, M. Isabel Muro-Pastor (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12853614.txt.
Description
A carbon gatekeeper can steer sugar output in sun-eating bacteria, Maria Teresa Dominguez-Lobo and co-authors show in a 2025 study. Cyanobacteria make chemicals from sunlight and air, but most carbon flows into growth rather than product. The regulator CfrA normally diverts carbon into storage starch when nitrogen runs low.
The test species stores sugar and a salty solute under salt stress. Tuning the regulator's expression aims to push more carbon toward sugar release. Sugar from such bacteria can feed partner microbes in joint cultures. Rerouting by regulation, not just gene swaps, widens the toolbox for solar chemical factories.
Catalog record
| CREATOR | María Teresa Domínguez-Lobo, Pablo Ortega-Martínez, Francisco J. Florencio, M. Isabel Muro-Pastor |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 67 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |