Ammonia as a weak base for continuous-flow synthesis of Au, Pd, and Cu-NHC heteroleptic chloro complexes
Riku Saito, Andreas Simoens, Celle Vandersteen, Christian V Stevens, Steven P Nolan · 2025
Read Ammonia as a weak base for continuous-flow synthesis of Au, Pd, and Cu-NHC heteroleptic chloro complexes by Riku Saito, Andreas Simoens, Celle Vandersteen, Christian V Stevens, Steven P Nolan (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12852678.txt.
Description
Riku Saito and co-authors report chemistry research from two thousand twenty-five on making metal complexes in a flowing system rather than in batches. The complexes pair gold, palladium, or copper with a class of carbon-based ligands called NHCs, and each also carries a chlorine partner. Such complexes are prized tools in synthesis.
Weak, cheap bases are a favored way to assemble them. The team shows that ammonia, used as a gas or dissolved in water, can serve as that base inside a continuous-flow setup. Because the mixture stays fully uniform, the reactions run under milder conditions, finish faster, and work at higher concentration than leading batch methods. The authors present the flow route as a cleaner path to these useful complexes.
Catalog record
| CREATOR | Riku Saito, Andreas Simoens, Celle Vandersteen, Christian V Stevens, Steven P Nolan |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 31 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |