Comparative evaluation of standardized imaging-guided contact selection for subthalamic deep brain stimulation in Parkinson’s disease: study protocol for a randomized double-blind crossover trial
G A Brandt, L Piotrowsky, J N Petry-Schmelzer, C van der Linden, C Schedlich-Teufer, V Visser-Vandewalle, T A Dembek, M T Barbe · 2025
Read Comparative evaluation of standardized imaging-guided contact selection for subthalamic deep brain stimulation in Parkinson’s disease: study protocol for a randomized double-blind crossover trial by G A Brandt, L Piotrowsky, J N Petry-Schmelzer, C van der Linden, C Schedlich-Teufer, V Visser-Vandewalle, T A Dembek, M T Barbe (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12849625.txt.
Description
Deep brain stimulation calms Parkinson's symptoms, but choosing which contact on the wire to activate still relies on slow bedside testing. G Brandt and co-authors set out in 2025 a trial protocol comparing that habit against selection guided by brain imaging.
Thirty patients with wires in both sides of the brain will try each approach for a week, in random order, with neither patient nor assessor knowing which is active. The main outcome is simply which week the patient prefers. Movement scores, wrist motion sensors, and quality-of-life questionnaires back it up. The team argues patient preference catches gains that standard scales miss.
Catalog record
| CREATOR | G A Brandt, L Piotrowsky, J N Petry-Schmelzer, C van der Linden, C Schedlich-Teufer, V Visser-Vandewalle, T A Dembek, M T Barbe |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 43 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |