Electroacupuncture alleviates blood-brain barrier disruption and neuroinflammation via astrocytic MC4R in a mouse model of multiple sclerosis
Yanping Wang, Xiaoru Ma, Zhixin Qiao, Xiyu Zhang, Jiayu Ji, Sifan Zhang, Wei Zhuang, Junfeng Wu, Anqi Li, Chao Wang, Xin Xiu, Jing Wang, Yanting Meng, Wei Huang, Xiujuan Lang, Xijun Liu, Bo Sun, Hulun Li, Yumei Liu · 2025
Read Electroacupuncture alleviates blood-brain barrier disruption and neuroinflammation via astrocytic MC4R in a mouse model of multiple sclerosis by Yanping Wang, Xiaoru Ma, Zhixin Qiao, Xiyu Zhang, Jiayu Ji, Sifan Zhang, Wei Zhuang, Junfeng Wu, Anqi Li, Chao Wang, Xin Xiu, Jing Wang, Yanting Meng, Wei Huang, Xiujuan Lang, Xijun Liu, Bo Sun, Hulun Li, Yumei Liu (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12849424.txt.
Description
Yanping Wang and co-authors report a 2025 study of electric needle treatment in mice with a model of multiple sclerosis. In this disease, immune attack inflames the brain and spine and breaks the barrier that guards them. Star-shaped support cells in the brain help drive that inflammation, so the team focused on them.
Treatment at a classic point eased barrier damage and inflammation at the disease peak. It also raised levels of a hormone and its receptor on those support cells. A drug that turns the receptor on copied the benefit, while blockers and gene silencing undid it. The chain gives a clear target for how the treatment works.
Catalog record
| CREATOR | Yanping Wang, Xiaoru Ma, Zhixin Qiao, Xiyu Zhang, Jiayu Ji, Sifan Zhang, Wei Zhuang, Junfeng Wu, Anqi Li, Chao Wang, Xin Xiu, Jing Wang, Yanting Meng, Wei Huang, Xiujuan Lang, Xijun Liu, Bo Sun, Hulun Li, Yumei Liu |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 48 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |