Ultrasound-responsive micro/nanobubbles based intelligent theranostic systems for precision tumor therapy

Deng Liu, Yi Ling, Wanqian Liu, Jun Deng, Yanli Guo · 2025

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Description

Tiny bubbles that burst under ultrasound can punch temporary holes in tumor defenses, letting drugs pour in where they are needed. Deng Liu and co-authors review this theranostic strategy in 2025: microbubbles and nanobubbles that both treat and help image the tumor. The review walks through how the bubbles oscillate, grow, and collapse, and what those forces do to vessels and cells.

That battering boosts chemotherapy, sound-activated drugs, immunotherapy, gene delivery, radiation, and iron-driven cell death, largely by raising drug levels inside the tumor while sparing the rest of the body. The authors close with the hurdles still blocking routine clinical use and where the field should push next.

Catalog record

CREATORDeng Liu, Yi Ling, Wanqian Liu, Jun Deng, Yanli Guo
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE101 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12849389

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