Molecular architecture of mesoderm cells across early to middle stage of human embryo development at single-cell resolution
Wei Zhang, Haiyan Yu, Zhibin Zhang, Dandan Li, Yane Yang, Wei Shi, Wenting Li, Yan Jiang, Wenlong Hu, Zhipeng Zeng, Xinqiong Liu, Zhanye Zheng, Minglin Ou, Donge Tang, Yong Dai · 2025
Read Molecular architecture of mesoderm cells across early to middle stage of human embryo development at single-cell resolution by Wei Zhang, Haiyan Yu, Zhibin Zhang, Dandan Li, Yane Yang, Wei Shi, Wenting Li, Yan Jiang, Wenlong Hu, Zhipeng Zeng, Xinqiong Liu, Zhanye Zheng, Minglin Ou, Donge Tang, Yong Dai (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12849250.txt.
Description
Wei Zhang and co-authors map middle-layer embryo cells at single-cell level in human embryos from seven to seventeen weeks, in a study from two thousand twenty-five. The layer seeds heart, kidney, spleen, liver, and brain support tissues. Gene reads plus open-chromatin reads trace how cell groups split toward each organ.
One gene, EGR1, looks tied to the split of mixed subgroups. One subgroup sat closest in profile to heart lining cells. Another held promise to form vessel lining and blood stem cells, with a second gene in play. The maps serve as a reference for regenerative work. Readers get lineage clues for early organ building.
Catalog record
| CREATOR | Wei Zhang, Haiyan Yu, Zhibin Zhang, Dandan Li, Yane Yang, Wei Shi, Wenting Li, Yan Jiang, Wenlong Hu, Zhipeng Zeng, Xinqiong Liu, Zhanye Zheng, Minglin Ou, Donge Tang, Yong Dai |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 72 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |