The roles and clinical applications of mesenchymal stem cells and their exosomes in hematologic diseases
Mengxue Deng, Xiaoying Zhang, Yicheng Zhang · 2025
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Description
Mengxue Deng, Xiaoying Zhang, and Yicheng Zhang review how mesenchymal stem cells and their tiny released packages, exosomes, are being used against blood diseases. These stem cells calm the immune system, fight inflammation, and help tissues repair. In blood medicine they can boost the take of transplanted blood stem cells and ease graft-versus-host disease.
The cells have also been tried in immune platelet disorders and severe aplastic anemia. In blood cancers their effect cuts both ways, sometimes aiding and sometimes opposing tumors. Exosomes copy many of the cells' benefits with better stability and less immune reaction, making them attractive for transplant care. The review details current uses and where the approach is heading.
Catalog record
| CREATOR | Mengxue Deng, Xiaoying Zhang, Yicheng Zhang |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 81 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |