Vaccine-preventable HPV burden and cervical abnormalities in women during 2022–2024 Octobre Rose campaigns in Libreville
Alfred K. F. Mabika-Obanda, Nathalie Ambounda Ledaga, Krystina Ngou Milama, Vénusia Zang Obame, Amel Kevin Alame-Emane, Adama Sanon, Corneille Ndong-Ella, Hugues Loemba, Laurent Bélec, Jean-Pierre Ngou Mve Ngou, Paulin N. Essone, Armel Mintsa-Ndong, Ralph-Sydney Mboumba Bouassa, Joël Fleury Djoba Si · 2025
Read Vaccine-preventable HPV burden and cervical abnormalities in women during 2022–2024 Octobre Rose campaigns in Libreville by Alfred K. F. Mabika-Obanda, Nathalie Ambounda Ledaga, Krystina Ngou Milama, Vénusia Zang Obame, Amel Kevin Alame-Emane, Adama Sanon, Corneille Ndong-Ella, Hugues Loemba, Laurent Bélec, Jean-Pierre Ngou Mve Ngou, Paulin N. Essone, Armel Mintsa-Ndong, Ralph-Sydney Mboumba Bouassa, Joël Fleury Djoba Si (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12847706.txt.
Description
Cervical cancer kills many women in sub-Saharan Africa, and persistent infection with cancer-causing types of human papillomavirus drives most cases. Alfred Mabika-Obanda and co-authors screened 1,524 women during three years of Octobre Rose campaigns in Libreville, Gabon. They combined visual inspection of the cervix with laboratory typing of the virus. Overall, 21 percent of women carried the virus, and 18.5 percent carried cancer-causing types.
Type 35 was the single commonest type, yet the nine-valent vaccine's target types caused 63 percent of cancer-causing infections and most detected abnormalities, led by types 16 and 45. HIV infection and high lifetime sexual exposure raised the odds of carrying a risky type. The authors argue the vaccine could prevent much of this burden, while screening must continue for types it misses.
Catalog record
| CREATOR | Alfred K. F. Mabika-Obanda, Nathalie Ambounda Ledaga, Krystina Ngou Milama, Vénusia Zang Obame, Amel Kevin Alame-Emane, Adama Sanon, Corneille Ndong-Ella, Hugues Loemba, Laurent Bélec, Jean-Pierre Ngou Mve Ngou, Paulin N. Essone, Armel Mintsa-Ndong, Ralph-Sydney Mboumba Bouassa, Joël Fleury Djoba Si |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 51 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |