The Forgotten History of Bacteriophages in Bulgaria: An Overview and Molecular Perspective on Their Role in Addressing Antibiotic Resistance and Therapy
Nikolay Kalvatchev, Tannaz Khanbabapour, Arit Sakkeer, Iliya Tsekov, Yancho Delchev, Tanya Strateva · 2025
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Description
Nikolay Kalvatchev and co-authors recover a forgotten chapter of virus-based medicine from Bulgarian archives. Bacteriophages, viruses that eat bacteria, are back in fashion as antibiotics fail. This review gathers what Bulgarian researchers documented through the nineteen sixties, seventies, and eighties, an era when the West had largely shelved phage therapy.
The survey moves from phage structure and killing mechanisms to the Bulgarian clinical record, weighing old findings against modern standards of safety and proof. It connects those results to today's fights against resistant infections and asks what the Bulgarian experience still teaches about putting phages into practice. The authors close with a program: international collaboration, infrastructure, and supportive policy to make phage therapy a routine weapon.
Catalog record
| CREATOR | Nikolay Kalvatchev, Tannaz Khanbabapour, Arit Sakkeer, Iliya Tsekov, Yancho Delchev, Tanya Strateva |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 75 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |