A Novel Recombinant Chicken-Derived H6N8 Subtype Avian Influenza Virus Caused Disease in Chickens and Mice
Yafen Song, Shengyao Song, Aoyang Yan, Hongxuan Gong, Huan Yang, Feihu Guan, Min Zhang, Bing Zhang, Qianyi Zhang, Chenghuai Yang, Guanlong Xu · 2025
Read A Novel Recombinant Chicken-Derived H6N8 Subtype Avian Influenza Virus Caused Disease in Chickens and Mice by Yafen Song, Shengyao Song, Aoyang Yan, Hongxuan Gong, Huan Yang, Feihu Guan, Min Zhang, Bing Zhang, Qianyi Zhang, Chenghuai Yang, Guanlong Xu (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12846371.txt.
Description
Yafen Song and co-authors characterize a new stitched-together bird flu found on a chicken farm in southern China in this 2025 paper. The H6 family of avian influenza spreads widely in birds and keeps edging toward mammals, which worries health watchers. This isolate, an H6N8 from 2023, carries genes from three sources.
Its surface genes trace to Eurasian H6 lines and a North American partner, while all six inner genes came from the H9N2 family common in Chinese poultry. The virus carries several markers tied to wider host range and stronger disease. In mice it infected without any warmup, multiplied in lungs and noses, spread through the body, and killed. Chickens showed no illness yet shed the virus from both ends and passed it to cage mates, building strong antibodies. The authors flag the strain as a quiet public health risk.
Catalog record
| CREATOR | Yafen Song, Shengyao Song, Aoyang Yan, Hongxuan Gong, Huan Yang, Feihu Guan, Min Zhang, Bing Zhang, Qianyi Zhang, Chenghuai Yang, Guanlong Xu |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 25 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |