Prevention of Transfusion-Transmitted Malaria and Chagas Disease in Non-Endemic Countries: An 8-Year Study of Seroprevalence Among Donors at Risk in Tuscany (Central Italy)
Valentina D. Mangano, Barbara Pinto, Roberto Marotta, Luca Galli, Giovanna Antonella Moscato, Antonella Lupetti, Fabrizio Bruschi · 2025
Read Prevention of Transfusion-Transmitted Malaria and Chagas Disease in Non-Endemic Countries: An 8-Year Study of Seroprevalence Among Donors at Risk in Tuscany (Central Italy) by Valentina D. Mangano, Barbara Pinto, Roberto Marotta, Luca Galli, Giovanna Antonella Moscato, Antonella Lupetti, Fabrizio Bruschi (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12845420.txt.
Description
Valentina Mangano and co-authors report eight years of blood donor screening for two parasite diseases in Tuscany, Italy, in a 2025 study. Malaria and Chagas disease can pass to patients through donated blood, so Italy screens donors with travel or birth links to regions where the parasites circulate. The Pisa lab ran these checks from 2016 onward.
Of 3,754 donors tested for malaria antibodies, 6.8 percent came back positive, with the highest rates in donors from sub-Saharan Africa. None of the positive donors who took a DNA test had a live infection, and many lost their antibody signal within a year. For Chagas disease, 0.7 percent of 4,285 donors tested positive. Rates dipped in 2020, when travel fell during the pandemic. The results show screening can catch past exposure while live infection stays rare.
Catalog record
| CREATOR | Valentina D. Mangano, Barbara Pinto, Roberto Marotta, Luca Galli, Giovanna Antonella Moscato, Antonella Lupetti, Fabrizio Bruschi |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 23 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |