Recursive Ectopic Gene Conversion Leads to Elevated DNA Mutation, Gene Loss, and Novel Gene Formation in Aspergillus
Ruojin Wang, Weiwei Liu, Tao Liu, Tianmeng Wang, Huilong Chen, Huilong Qi, Jiangli Wang, Meifang Lan, Xiyin Wang · 2025
Read Recursive Ectopic Gene Conversion Leads to Elevated DNA Mutation, Gene Loss, and Novel Gene Formation in Aspergillus by Ruojin Wang, Weiwei Liu, Tao Liu, Tianmeng Wang, Huilong Chen, Huilong Qi, Jiangli Wang, Meifang Lan, Xiyin Wang (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12844118.txt.
Description
Gene swapping that speeds change in a fungus is traced by Ruojin Wang and co-authors in work dated 2025. Gene conversion can copy one gene stretch over a kin stretch, which shifts counts and breeds new genes. The process was barely known in Aspergillus, a fungus group with farm and health weight. The team studied matched gene sets on one chromosome of two kin species.
Family trees showed swaps ran often between far-apart kin genes in each species. Swapped zones held more point changes and more lost DNA than calm zones. Some genes split into shorter new genes, then swaps spread that split. A DNA loop in their shared ancestor may drive the swaps.
Catalog record
| CREATOR | Ruojin Wang, Weiwei Liu, Tao Liu, Tianmeng Wang, Huilong Chen, Huilong Qi, Jiangli Wang, Meifang Lan, Xiyin Wang |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 32 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |