Mg Alloys Reduce Gastric Cancer and Mediate Therapeutic Management of Antibacterial Function
Yonghong Wu, Xiaoyun Lu, Yiwei Wang, Guangyan Liu, Biao Yang · 2025
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Description
Yonghong Wu and co-authors test magnesium alloys as a two-front weapon against stomach cancer, in a 2025 preclinical study. The alloys were screened on gastric cancer cells, their effects traced with RNA sequencing, and wires of the material were implanted in mice carrying tumors. The same alloys were also challenged against two common pathogenic bacteria.
Growing cancer cells with the alloy cut their viability, and implanted wires shrank relative tumor volume by about forty-three percent. Gene readouts confirmed broad expression changes behind the effect. Bacterial growth fell by roughly seventy percent for both species tested. The authors propose the alloys as a fresh therapeutic resource, while noting the work is still at the animal and cell stage.
Catalog record
| CREATOR | Yonghong Wu, Xiaoyun Lu, Yiwei Wang, Guangyan Liu, Biao Yang |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 29 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |