Combined Transcriptomic and Metabolomic Analyses of the Response of Ganoderma lucidum to Elevated CO2
Tingting Fang, Lu Chen, Hui Yao, Ye Li, Guohui Liu, Shaofeng Wu, Jin Lan, Xiangdong Chen · 2025
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Description
Tingting Fang and co-authors probed how raised carbon dioxide reshapes a medicinal fungus in a 2025 study. High carbon dioxide in cultivation often makes the fungus Ganoderma lucidum grow antler-shaped fruiting bodies instead of normal caps. The molecular response behind that change was unclear.
Gene activity and metabolite profiles were compared across three growth stages under normal and raised gas levels. Hundreds of metabolites shifted at each stage. Amino acid production fell broadly, while certain triterpenoids and steroids built up. At a key stage, genes for cell division and DNA repair were suppressed, which may block normal cap growth. Genes for sensing the gas and remodelling cell walls also changed, sketching the antler pathway.
Catalog record
| CREATOR | Tingting Fang, Lu Chen, Hui Yao, Ye Li, Guohui Liu, Shaofeng Wu, Jin Lan, Xiangdong Chen |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 47 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |