Fecal Microbiota Transplantation for Autism Spectrum Disorder in Children: Results from a Prospective Open-Label Controlled Observational Study
Dominykas Varnas, Arnas Kunevičius, Aurelijus Burokas, Vaidotas Urbonas · 2025
Read Fecal Microbiota Transplantation for Autism Spectrum Disorder in Children: Results from a Prospective Open-Label Controlled Observational Study by Dominykas Varnas, Arnas Kunevičius, Aurelijus Burokas, Vaidotas Urbonas (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12842803.txt.
Description
Varnas and co-authors try transplanting gut microbes into children with autism to see whether it eases symptoms. Imbalances in gut bacteria are suspected to play a role in autism, and fecal microbiota transplantation from a healthy donor is one proposed way to reset the gut.
Thirty children took part, fifteen receiving one transplant by colonoscopy and fifteen serving as controls, with behavior and gut symptoms scored over time. The main observational score, ADOS, did not improve more than in controls. However, parent-rated and clinician-rated scales improved clearly at eight weeks, and some gains lasted many months. No serious side effects appeared. The authors call the results exploratory and ask for larger blinded trials.
Catalog record
| CREATOR | Dominykas Varnas, Arnas Kunevičius, Aurelijus Burokas, Vaidotas Urbonas |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 41 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |