Effects of Dichrostachys glomerata and Cissus quadrangularis Extracts on GLP-1 Secretion and DPP-4 Activity in Overweight and Obese Individuals: A Randomized Controlled Trial

Janvier Youovop, Guy Takuissu, Régine Minoue, Felix Nwang, Maryam Adegboyega, Crista Arrey, Inelle Makamwe, Julius Oben · 2025

Read Effects of Dichrostachys glomerata and Cissus quadrangularis Extracts on GLP-1 Secretion and DPP-4 Activity in Overweight and Obese Individuals: A Randomized Controlled Trial by Janvier Youovop, Guy Takuissu, Régine Minoue, Felix Nwang, Maryam Adegboyega, Crista Arrey, Inelle Makamwe, Julius Oben (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12842617.txt.

Description

Janvier Youovop and co-authors run a controlled trial, published in twenty twenty-five, of two plant extracts long used in Cameroon for weight loss. The extracts come from Dichrostachys glomerata and Cissus quadrangularis. The team asked whether they raise GLP-1, a gut hormone that curbs hunger, and slow the enzyme that breaks it down.

The trial ran sixteen weeks with two hundred forty-eight adults who were overweight or obese. Groups took one extract, the drug semaglutide, or a placebo pill each day. Both extract groups showed higher GLP-1 and lower enzyme activity than the placebo group. They also lost weight and body fat, ate less, and felt fuller. The authors present the plants as aids worth further study.

Catalog record

CREATORJanvier Youovop, Guy Takuissu, Régine Minoue, Felix Nwang, Maryam Adegboyega, Crista Arrey, Inelle Makamwe, Julius Oben
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE25 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12842617

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