Developmental and Stress-Mediated Transcriptional Shifts in Riboflavin Metabolism Pathway in Arabidopsis

Dikran Tsitsekian, Panagiota Mylona, Efstratios Kamargiakis, Stamatis Rigas, Gerasimos Daras · 2025

Read Developmental and Stress-Mediated Transcriptional Shifts in Riboflavin Metabolism Pathway in Arabidopsis by Dikran Tsitsekian, Panagiota Mylona, Efstratios Kamargiakis, Stamatis Rigas, Gerasimos Daras (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12840815.txt.

Description

Dikran Tsitsekian, Panagiota Mylona, and three colleagues chart when and where a model plant switches on the genes that make vitamin B2, in a paper published in two thousand twenty-five. The vitamin, riboflavin, is the raw material for two cofactors that power photosynthesis, respiration, and nitrogen use. Plants brew their own; animals must eat theirs.

The chemistry of the pathway was well mapped, but its regulation was not. The team mined large gene expression datasets for the thale cress Arabidopsis, adding co-expression analysis and a scan of the switches in front of each gene. They also measured actual flavin levels by chromatography as plants developed and faced stress. Expression shifted with both development and stress, in patterns the paper catalogs. Knowing how a plant tunes its vitamin supply matters for breeding and biofortification. It also completes a pathway biochemists thought they had finished.

Catalog record

CREATORDikran Tsitsekian, Panagiota Mylona, Efstratios Kamargiakis, Stamatis Rigas, Gerasimos Daras
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE30 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12840815

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