Broccoli Extract (Broccoli NMN®) Improves Skin Hydration by Regulating HAS and NF-κB Pathways and Reduces Wrinkle Formation via the TGF-βR1/Smad3/Collagen Pathway
Wonhee Cho, Yeonhwa Lee, Minhee Lee, Jeongjin Park, Yuki Mukai, Dae Soo Lim, Hyelin Jeon, Woojin Jun · 2025
Read Broccoli Extract (Broccoli NMN®) Improves Skin Hydration by Regulating HAS and NF-κB Pathways and Reduces Wrinkle Formation via the TGF-βR1/Smad3/Collagen Pathway by Wonhee Cho, Yeonhwa Lee, Minhee Lee, Jeongjin Park, Yuki Mukai, Dae Soo Lim, Hyelin Jeon, Woojin Jun (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12839681.txt.
Description
A broccoli extract rich in a vitamin-like compound may protect skin from sun damage, easing dryness, wrinkles, and dark spots. Wonhee Cho and co-authors tested the extract in this 2025 study using cell and animal models exposed to ultraviolet light. Treated skin held up far better than untreated skin on several measures.
The extract raised the activity of pathways that build skin moisture and its protective barrier. It also boosted the collagen pathway that keeps skin firm, while damping inflammation signals. Sun-driven aging is a main target of the skin care market, and most products are tested only for surface effects. Showing the inner pathways gives this ingredient a firmer scientific footing, though human skin trials remain the real test.
Catalog record
| CREATOR | Wonhee Cho, Yeonhwa Lee, Minhee Lee, Jeongjin Park, Yuki Mukai, Dae Soo Lim, Hyelin Jeon, Woojin Jun |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 29 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |