The Current State of Mock Circulatory Loop Applications in Aortic and Cardiovascular Research: A Scoping Review
Felix E. N. Osinga, Nesar A. Hasami, Jasper F. de Kort, Emma-Lena Maris, Maurizio Domanin, Martina Schembri, Alessandro Caimi, Michele Conti, Constantijn E. V. B. Hazenberg, Ferdinando Auricchio, Jorg L. de Bruin, Joost A. van Herwaarden, Santi Trimarchi · 2025
Read The Current State of Mock Circulatory Loop Applications in Aortic and Cardiovascular Research: A Scoping Review by Felix E. N. Osinga, Nesar A. Hasami, Jasper F. de Kort, Emma-Lena Maris, Maurizio Domanin, Martina Schembri, Alessandro Caimi, Michele Conti, Constantijn E. V. B. Hazenberg, Ferdinando Auricchio, Jorg L. de Bruin, Joost A. van Herwaarden, Santi Trimarchi (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12839285.txt.
Description
Before a heart device or repair reaches a patient, it often runs on a benchtop loop that mimics the circulation. Felix Osinga and co-authors map that whole practice in a 2025 review. Eighty-four studies of aorta simulation met their screen. Most loops drove printed or molded plastic aortas, though pig vessels were common too.
The work fell into themes: tissue mechanics, flow behavior, device testing, imaging checks, and a single training use. Loops probed stiffness, tear spread, leaks around grafts, and scanner accuracy. The authors call for shared reporting standards so results from different rigs can be compared and carried toward patient care.
Catalog record
| CREATOR | Felix E. N. Osinga, Nesar A. Hasami, Jasper F. de Kort, Emma-Lena Maris, Maurizio Domanin, Martina Schembri, Alessandro Caimi, Michele Conti, Constantijn E. V. B. Hazenberg, Ferdinando Auricchio, Jorg L. de Bruin, Joost A. van Herwaarden, Santi Trimarchi |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 36 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |