Protein S-Palmitoylation as Potential Therapeutic Target for Dermatoses
Yanhai Feng, Jianxin Wu, Hui Tang, Shunying Liu, Honglin Jia, Yi Liang, Zhenglin Li, Lingbo Li, Lingfei Li, Xia Lei · 2025
Read Protein S-Palmitoylation as Potential Therapeutic Target for Dermatoses by Yanhai Feng, Jianxin Wu, Hui Tang, Shunying Liu, Honglin Jia, Yi Liang, Zhenglin Li, Lingbo Li, Lingfei Li, Xia Lei (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12838948.txt.
Description
Yanhai Feng and co-authors review a protein tagging process as a drug target for skin disease in a 2025 paper. The process attaches a fat molecule to proteins, which steers where they sit in the cell and how long they last. A family of enzymes drives the tagging, and a reverse step removes the tag.
In skin, the tag cycle shapes inflammation, barrier strength, hair growth, and pigment output. Faults in the cycle are tied to hair loss, psoriasis, and other skin disorders. New lab tools now let teams map tagged proteins in detail. The review sums up what is known and weighs drug ideas that block or boost the tagging enzymes for future skin care.
Catalog record
| CREATOR | Yanhai Feng, Jianxin Wu, Hui Tang, Shunying Liu, Honglin Jia, Yi Liang, Zhenglin Li, Lingbo Li, Lingfei Li, Xia Lei |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 44 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |