A meta analysis of pulmonary vein isolation compared with additional ablation strategies for atrial fibrillation

Muhammad M. Saleem, Muhammad Mudassar, Ajit Brar, Aleena Usman, Gurparvesh Goraya, Sameen B. Butt, Sohail Sodhi, Soumiya Ravi, Keerat Bains, Vijyawant Brar · 2025

Read A meta analysis of pulmonary vein isolation compared with additional ablation strategies for atrial fibrillation by Muhammad M. Saleem, Muhammad Mudassar, Ajit Brar, Aleena Usman, Gurparvesh Goraya, Sameen B. Butt, Sohail Sodhi, Soumiya Ravi, Keerat Bains, Vijyawant Brar (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12837986.txt.

Description

Muhammad M Saleem and co-authors weigh whether extra burning helps when doctors ablate a fibrillating heart. The standard fix, pulmonary vein isolation, seals the veins that trigger atrial fibrillation. Yet the rhythm often returns, so some teams add lines of burns, seal the back wall, or chase stray signals. Trial results for those extras have swung both ways.

The review gathers only randomized trials that pit isolation alone against isolation plus extras, or against other strategies. Patients had either the persistent or the paroxysmal form of the disease. A random-effects pooling then compares freedom from the rhythm across strategies, with subgroups for each add-on type. The authors aim to tell operators which extras, if any, earn their burns.

Catalog record

CREATORMuhammad M. Saleem, Muhammad Mudassar, Ajit Brar, Aleena Usman, Gurparvesh Goraya, Sameen B. Butt, Sohail Sodhi, Soumiya Ravi, Keerat Bains, Vijyawant Brar
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE62 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12837986

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