Understanding and Advancing Wound Healing in the Era of Multi-Omic Technology
Serena L. Jing, Elijah J. Suh, Kelly X. Huang, Michelle F. Griffin, Derrick C. Wan, Michael T. Longaker · 2025
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Description
Serena Jing and co-authors review how reading many layers of biology at once is changing wound care. Healing a wound takes many cell types acting in sequence, and when the process stalls, chronic wounds or heavy scars result. Older studies read one layer at a time, such as genes or proteins, and so missed how the layers interact. Their review appeared in 2025.
New tools read several layers in single cells and in place on the tissue. They have found subtypes of fibroblast cells that either scar or truly regrow skin, and chats between immune and surface cells that drive closure. Computer models and artificial intelligence now help merge these data and predict how a wound will heal. Costs and data handling remain hurdles, but the authors see tailored wound treatment coming.
Catalog record
| CREATOR | Serena L. Jing, Elijah J. Suh, Kelly X. Huang, Michelle F. Griffin, Derrick C. Wan, Michael T. Longaker |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 52 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |