Genetic Analysis of Virulence and β-Lactamase Determinants Related to β-Lactamase Inhibitors in Pseudomonas aeruginosa Strains from Nosocomial Infections
Gloria Luz Paniagua-Contreras, Elizabeth Olvera-Navarro, Jennefer Paloma Herrera-Gabriel, Laura Verónica González-Vega, Luis Rey García-Cortés, Moisés Moreno-Noguez, Héctor Martínez-Gregorio, Felipe Vaca-Paniagua, Ana María Fernández-Presas, Eric Monroy-Pérez · 2025
Read Genetic Analysis of Virulence and β-Lactamase Determinants Related to β-Lactamase Inhibitors in Pseudomonas aeruginosa Strains from Nosocomial Infections by Gloria Luz Paniagua-Contreras, Elizabeth Olvera-Navarro, Jennefer Paloma Herrera-Gabriel, Laura Verónica González-Vega, Luis Rey García-Cortés, Moisés Moreno-Noguez, Héctor Martínez-Gregorio, Felipe Vaca-Paniagua, Ana María Fernández-Presas, Eric Monroy-Pérez (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12837615.txt.
Description
Gloria Luz Paniagua-Contreras and nine colleagues profile the virulence and drug-resistance genes of 124 Pseudomonas aeruginosa strains taken from Mexican patients. This germ causes infections picked up in hospitals and out in the community. More and more, it defeats the antibiotic pairs that were built to block its enzymes, and doctors watch it with care. The team set out to map what these strains carry and what still works against them.
Nearly all strains carried genes for proteases, phospholipases, elastases, and signaling systems. Every strain resisted at least one inhibitor pair, and over half resisted piperacillin-tazobactam. The group mapped how these gene patterns link with resistance genes and with bacterial family groups. Such profiles show why this germ is so dangerous in hospitals. They also point to which drug pairs remain worth trusting.
Catalog record
| CREATOR | Gloria Luz Paniagua-Contreras, Elizabeth Olvera-Navarro, Jennefer Paloma Herrera-Gabriel, Laura Verónica González-Vega, Luis Rey García-Cortés, Moisés Moreno-Noguez, Héctor Martínez-Gregorio, Felipe Vaca-Paniagua, Ana María Fernández-Presas, Eric Monroy-Pérez |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 33 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |