Combination therapy with mineralocorticoid receptor antagonists and SGLT2 inhibitors versus SGLT2 inhibitor monotherapy in chronic kidney disease: an updated meta-analysis of randomized controlled trials
Shaikh Muhammad Daniyal, Hareem Ajaz, Minahil Riaz, Naveen Murad Khatoon, Zunaira Aftab, Habiba Tauqir Gondal, Isbah Gul, Mahwish Sarwar, Fizza Batool, Syeda Laiba Fahim, Amna Noor, Ayan Khalid, Danish Ali Ashraf, Romal Jabarkhil · 2025
Read Combination therapy with mineralocorticoid receptor antagonists and SGLT2 inhibitors versus SGLT2 inhibitor monotherapy in chronic kidney disease: an updated meta-analysis of randomized controlled trials by Shaikh Muhammad Daniyal, Hareem Ajaz, Minahil Riaz, Naveen Murad Khatoon, Zunaira Aftab, Habiba Tauqir Gondal, Isbah Gul, Mahwish Sarwar, Fizza Batool, Syeda Laiba Fahim, Amna Noor, Ayan Khalid, Danish Ali Ashraf, Romal Jabarkhil (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12837365.txt.
Description
Shaikh Muhammad Daniyal and a team of co-authors present a 2025 pooled study of paired drug care for chronic kidney disease. Two drug classes each help the kidney on their own. The question is whether using both beats one alone. They pool five trials with about eight hundred patients.
Paired care cut protein in urine far more than single care. It also lowered blood pressure more. A kidney function measure dipped slightly, a known early effect. High potassium risk rose, but serious side effects did not. The authors back the pairing as promising. They call for large, long trials to test hard outcomes like kidney failure and death.
Catalog record
| CREATOR | Shaikh Muhammad Daniyal, Hareem Ajaz, Minahil Riaz, Naveen Murad Khatoon, Zunaira Aftab, Habiba Tauqir Gondal, Isbah Gul, Mahwish Sarwar, Fizza Batool, Syeda Laiba Fahim, Amna Noor, Ayan Khalid, Danish Ali Ashraf, Romal Jabarkhil |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 33 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |