Influence of caloric restriction history, intermittent exposure to palatable food and sex in a binge eating model in C57BL/6J mice

Nuria Morales-Puerto, Clémence Fayt, Chloé Tezenas du Montcel, Amandine Everard · 2025

Read Influence of caloric restriction history, intermittent exposure to palatable food and sex in a binge eating model in C57BL/6J mice by Nuria Morales-Puerto, Clémence Fayt, Chloé Tezenas du Montcel, Amandine Everard (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12837107.txt.

Description

Dieting history and the rhythm of treats shape binge eating in mice, in a 2025 study by Nuria Morales-Puerto and co-authors. Binge eating disorder has a tangled biology, and animal models let researchers vary one trigger at a time.

Male and female mice got two hours of access to a high-fat, high-sugar diet while already fed, either daily or every other day. Some groups had first lived through spells of calorie restriction. Both sexes developed binge-like eating under these setups. Brain tissue from the striatum was then checked for marker genes tied to three signaling chemicals: dopamine, glutamate, and GABA. The work compares which trigger, schedule or dieting past, drives the behavior and the brain changes hardest.

Catalog record

CREATORNuria Morales-Puerto, Clémence Fayt, Chloé Tezenas du Montcel, Amandine Everard
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE48 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12837107

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