Extracellular vesicles for macrophage reprogramming: an emerging paradigm in immunomodulatory therapeutics
Ha Young Jo, Min Kyeong Kim, Kyeong Tae Kim, Chanwoo Choi, Won Jong Rhee · 2025
Read Extracellular vesicles for macrophage reprogramming: an emerging paradigm in immunomodulatory therapeutics by Ha Young Jo, Min Kyeong Kim, Kyeong Tae Kim, Chanwoo Choi, Won Jong Rhee (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12837104.txt.
Description
Jo, Kim, Kim, Choi, and Rhee review in twenty twenty-five how tiny cell-made parcels can reprogram macrophages, the immune cells that switch between attack and calm states. That switch shapes diseases from cancer to long-term swelling. The parcels, shed by cells, carry signals that can flip the switch, but the exact pathways and best medical uses are still being worked out.
The review maps the signal pathways the parcels affect and sums up results in disease models. It also covers ways to load the parcels with cargo or coat them for better aim. Hurdles for clinic use include standard making, safety, and immune reactions. The authors see strong promise with much still to prove.
Catalog record
| CREATOR | Ha Young Jo, Min Kyeong Kim, Kyeong Tae Kim, Chanwoo Choi, Won Jong Rhee |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 132 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |