The effect of a sustainable diet and time-restricted eating and probiotic in heart failure with reduced ejection fraction patients: study protocol for a randomized, double-blind, and placebo-controlled trial

Pegah Rahbarinejad, Sara Amini, Asma Afshari, Seyyed Reza Sobhani, Kayvan Sadri, Golnaz Ranjbar, Majid Khadem Rezaiyan, Farveh Vakilian, Mohammad Hadi Eskandari, Reza Rezvani · 2025

Read The effect of a sustainable diet and time-restricted eating and probiotic in heart failure with reduced ejection fraction patients: study protocol for a randomized, double-blind, and placebo-controlled trial by Pegah Rahbarinejad, Sara Amini, Asma Afshari, Seyyed Reza Sobhani, Kayvan Sadri, Golnaz Ranjbar, Majid Khadem Rezaiyan, Farveh Vakilian, Mohammad Hadi Eskandari, Reza Rezvani (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12837078.txt.

Description

Pegah Rahbarinejad and nine co-authors publish in 2025 the protocol for a trial mixing sustainable diet, time-restricted eating, and a probiotic in heart failure with weakened pumping. Diet patterns and gut health are both tied to how this syndrome unfolds. The three-arm randomized trial runs 60 days in overweight or obese patients.

One arm pairs the diet and eating window with the probiotic Lactobacillus plantarum 299v. The second pairs them with a placebo, and a control arm completes the design, with 25 patients per group planned. Heart function and related markers are the readouts. Publishing the protocol in advance locks the design against quiet changes and lets other teams plan sister trials.

Catalog record

CREATORPegah Rahbarinejad, Sara Amini, Asma Afshari, Seyyed Reza Sobhani, Kayvan Sadri, Golnaz Ranjbar, Majid Khadem Rezaiyan, Farveh Vakilian, Mohammad Hadi Eskandari, Reza Rezvani
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE81 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12837078

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