Increased serum uric acid-to-urinary urate excretion ratio with the kidney function decline in male CKD patients without diabetes: a retrospective cohort study
Linjing Nie, Rui Peng, Xinhan Ying, Madiya Madeniyet, Dexian Zhang, Sijie Tao, Shiheng Cui, Yujiang Bao, Fuju Zhao, Jing Xiao · 2025
Read Increased serum uric acid-to-urinary urate excretion ratio with the kidney function decline in male CKD patients without diabetes: a retrospective cohort study by Linjing Nie, Rui Peng, Xinhan Ying, Madiya Madeniyet, Dexian Zhang, Sijie Tao, Shiheng Cui, Yujiang Bao, Fuju Zhao, Jing Xiao (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12837049.txt.
Description
Linjing Nie and co-authors study a uric acid ratio in chronic kidney disease in this 2025 paper. Uric acid links to kidney decline, but the connection is disputed. Their marker divides blood uric acid by the urate passed in urine over a day. Records covered 165 patients at a Shanghai hospital.
Kidney events meant losing half of filtration function, starting replacement therapy, or death. Analysis covered the whole group and subgroups by sex and diabetes status. The signal in the title appeared in men without diabetes. Higher ratios tracked with worse kidney outcomes there. Receiver curves tested how well the ratio separates patients who progress. A urine based ratio may flag risk that blood values alone miss.
Catalog record
| CREATOR | Linjing Nie, Rui Peng, Xinhan Ying, Madiya Madeniyet, Dexian Zhang, Sijie Tao, Shiheng Cui, Yujiang Bao, Fuju Zhao, Jing Xiao |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 32 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |