Impact of childhood trauma on depressive symptoms in bipolar adolescents: the mediating effect of sleep disturbance

Zhiying Wan, Yuan Hu, Yanfang Liu, Yue Sun, Zhongchun Liu, Meiyu Shen, Xiaofen Li · 2025

Read Impact of childhood trauma on depressive symptoms in bipolar adolescents: the mediating effect of sleep disturbance by Zhiying Wan, Yuan Hu, Yanfang Liu, Yue Sun, Zhongchun Liu, Meiyu Shen, Xiaofen Li (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12837043.txt.

Description

Wan and co-authors test whether poor sleep carries the effect of childhood trauma into depression in teens with bipolar disorder. Trauma in childhood worsens bipolar disorder in adolescence, above all by deepening depressive symptoms. The steps between early trauma and later depression, though, were still unclear to clinicians.

Sleep disturbance is a strong candidate for the middle step. The study enrolled 426 adolescents with bipolar disorder and measured trauma history, sleep quality, and depression severity. Statistical mediation tests checked if sleep problems explained the trauma link. A confirmed path would make sleep care a clear target for these teens.

Catalog record

CREATORZhiying Wan, Yuan Hu, Yanfang Liu, Yue Sun, Zhongchun Liu, Meiyu Shen, Xiaofen Li
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE28 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12837043

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