Aberrant brain functional network in COPD patients with cognitive impairment: clinical manifestations, mechanisms and therapeutic strategies

Jia-kai He, Xin-yu Han, Yun-sheng Tan, Zi-ang Yao, Yuan-li Dong, Cui-ling Feng · 2025

Read Aberrant brain functional network in COPD patients with cognitive impairment: clinical manifestations, mechanisms and therapeutic strategies by Jia-kai He, Xin-yu Han, Yun-sheng Tan, Zi-ang Yao, Yuan-li Dong, Cui-ling Feng (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12836923.txt.

Description

He and five co-authors review deranged brain networks in COPD patients with cognitive impairment, in work from 2025. Thinking problems are a common side effect of the lung disease, yet reviews had not tied them to brain network measures. The synthesis runs from symptoms through mechanisms and scan findings to candidate treatments, along a lung-brain axis.

Chronic low oxygen, inflammation and oxidative stress are cast as the main drivers of network damage. Deficits centre on executive function and visuospatial skill, with odd links between the default mode and visual networks. Long-term oxygen, anti-inflammatory care and cognitive rehabilitation each show some benefit, the authors report.

Catalog record

CREATORJia-kai He, Xin-yu Han, Yun-sheng Tan, Zi-ang Yao, Yuan-li Dong, Cui-ling Feng
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE69 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12836923

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