Production of the Bakırköy strain of sheeppox vaccine virus in spinner flasks using an alternative method with Cytodex 1 microcarriers on Vero cells
Görkem Çolak, Serdar Uzar, Meral Birbir · 2025
Read Production of the Bakırköy strain of sheeppox vaccine virus in spinner flasks using an alternative method with Cytodex 1 microcarriers on Vero cells by Görkem Çolak, Serdar Uzar, Meral Birbir (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12831445.txt.
Description
Görkem Çolak, Serdar Uzar, and Meral Birbir published a 2025 study on making sheeppox vaccine in a new way. Sheeppox is a fast-spreading virus disease that harms sheep and goats and costs farmers a lot. Vaccines control it, but the usual flat-layer cell method is hard to scale up.
The team grew Vero cells on tiny beads called Cytodex 1 microcarriers inside spinning flasks. They then infected the cells with the Bakırköy vaccine strain of the virus at two dose levels. Growth, cell health, and virus yield were tracked through the run. The goal is a method that can make much more vaccine in the same space.
Catalog record
| CREATOR | Görkem Çolak, Serdar Uzar, Meral Birbir |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 35 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |