Electroacupuncture alleviates central post-stroke pain in rats by modulating miR-21-5p/TGF-β/Smads pathway
Guihua Tian, Yang Wu, Zhihao Shang, Nan An, Huifeng Hao, Ke He, Youxiang Su, Luyu Yang, Meiyue Wang, Xinyi Li · 2025
Read Electroacupuncture alleviates central post-stroke pain in rats by modulating miR-21-5p/TGF-β/Smads pathway by Guihua Tian, Yang Wu, Zhihao Shang, Nan An, Huifeng Hao, Ke He, Youxiang Su, Luyu Yang, Meiyue Wang, Xinyi Li (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12825287.txt.
Description
Guihua Tian and colleagues show electroacupuncture easing stroke centre pain in rats, in work from 2025. Central pain after stroke resists most current drug care in clinic practice. A small RNA and its growth factor pathway stood accused in pain biology before now.
Needle current cut pain while lowering the small RNA in the injured brain zone. A partner protein rose, and growth factor signals plus inflammation marks fell together. Blocking the RNA alone also eased pain in the rat model tests. Forcing the RNA up or its partner down cancelled the needle benefit fully. The chain gives needle analgesia a clear molecular story in rats.
Catalog record
| CREATOR | Guihua Tian, Yang Wu, Zhihao Shang, Nan An, Huifeng Hao, Ke He, Youxiang Su, Luyu Yang, Meiyue Wang, Xinyi Li |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 42 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |