Comparison of gastric mucosa microbiota in metabolically healthy and unhealthy obesity
Bing Yan, Kun Zhang, Zi da Ma, Chengkun Qin · 2025
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Description
Bing Yan, Kun Zhang, Zida Ma, and Chengkun Qin compared stomach lining microbes between two kinds of obesity, in a study published in 2025. Some people with obesity stay metabolically healthy while others develop the usual complications, and gut microbes are implicated in the split. No one had checked the stomach's own microbial community. Using deep gene sequencing, the team profiled gastric samples from both groups.
The microbial profiles differed significantly between healthy and unhealthy obesity. Predicted microbial functions split too: thirty pathways differed, with several amino acid pathways turned up in the unhealthy group. Repair and protein-making machinery pathways ran higher in the healthy group. The authors say the stomach community mirrors metabolic state closely enough to suggest treatment targets. They frame the work as a first map of a neglected niche.
Catalog record
| CREATOR | Bing Yan, Kun Zhang, Zi da Ma, Chengkun Qin |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 33 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |