Subcortical nuclei and glymphatic system alterations in migraine with aura: a comparative 7T multimodal MRI analysis
Xinyu Wang, Yongqin Xiong, Xiu Liu, Xiaopeng Zong, Caohui Duan, Yuhan Wu, Xiangbing Bian, Song Wang, Jianxin Hu, Luhua Zhang, Haoxuan Lu, Bingbing Zhao, Jiayu Huang, Yan Li, Zhixuan Li, Zhao Dong, Xin Lou · 2025
Read Subcortical nuclei and glymphatic system alterations in migraine with aura: a comparative 7T multimodal MRI analysis by Xinyu Wang, Yongqin Xiong, Xiu Liu, Xiaopeng Zong, Caohui Duan, Yuhan Wu, Xiangbing Bian, Song Wang, Jianxin Hu, Luhua Zhang, Haoxuan Lu, Bingbing Zhao, Jiayu Huang, Yan Li, Zhixuan Li, Zhao Dong, Xin Lou (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12825203.txt.
Description
Migraine with aura announces itself with visual sparks before the pain, and its roots may reach below the brain's surface. Xinyu Wang and co-authors scan that deeper territory in a 2025 study using powerful 7-tesla MRI. Thirty-five patients with aura migraines, forty-five without aura, and thirty-nine healthy volunteers were compared.
The team measured activity synchrony, tissue volumes, iron-sensitive signals, and the brain's waste-clearing glymphatic system, including the spaces around vessels and a flow index. Both migraine groups showed quieter synchrony in memory and relay structures than healthy brains. Patients without aura tended toward smaller volumes in emotion regions such as the amygdala. The authors hunt for markers that separate the two migraine types, arguing the deep nuclei and drainage system deserve a place in the migraine story.
Catalog record
| CREATOR | Xinyu Wang, Yongqin Xiong, Xiu Liu, Xiaopeng Zong, Caohui Duan, Yuhan Wu, Xiangbing Bian, Song Wang, Jianxin Hu, Luhua Zhang, Haoxuan Lu, Bingbing Zhao, Jiayu Huang, Yan Li, Zhixuan Li, Zhao Dong, Xin Lou |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 56 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |